Widely Used Anticoagulation Drug Warfarin (Coumadin) More Dangerous Than Commonly Thought

Warfarin is an anticoagulation medicine that is one of the most widely prescribed medicines in the world. It is sold under a variety of brand names, the best known of them being Coumadin in the US. Warfarin is used widely … Continue reading

Nexrutine, An Anti-Inflammatory Supplement for Fighting Arthritis, Inflammation, and Prostate Cancer

Nexrutine is a herbal alternative to COX-2 inhibitors drugs such as aspirin and Celebrex. As a remedy for pain and soreness, it has a number of advantages over both broad COX-1/2 inhibitors like aspirin and selective COX-2 inhibitors like Celebrex. Nexrutine inhibits the inflammatory COX-2 connected with pain without inhibiting the protective COX-1, thereby having a lower risk of producing gastrointestinal and bleeding side effects versus aspirin and Celebrex. Other research shows that Nexrutine blocks the action not only COX-2, but also positively affects the inflammatory molecules TNF-a (Tumor Necrosis Factor alpha) and NF-kB (Nuclear Factor kappa B) that have been implicated along with COX-2 as participating in the development and spread of various cancers.

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