Low Vitamin K1 and K2 Levels Linked to Worse COVID-19 Outcomes

A new study entitled Reduced Vitamin K Status as A Potentially Modifiable Prognostic Risk Factor in COVID-19 indicates that low vitamin K levels may be connected to increased poor outcomes from COVID-19. Additionally, using drugs that impair vitamin K availability such as warfarin (Coumadin) may be increase risks.

The study explains coagulation disorders are common in COVID-19 and that vitamin K dependent biochemical processes are related to maintaining proper coagulation.

As there is little data on the use of common vitamin K antagonist (VKA) anti-coagulation medications such as warfarin and COVID-19, the authors point to how COVID-19 patients often develop lung damage resembling that in Idiopathic Pulmonary Fibrosis (IPF). They then refer to two studies on IPF patients that show very different outcomes likely due to their effects on vitamin K levels.

One study used short-term prednisolone (an anti-inflammatory drug) on patients, with some also receiving an anticoagulation drug (low molecular weight heparin). This approach achieved a much higher survival rate.

A second study used the long-term anticoagulant medication warfarin and had a much worse outcome, so much so that it was prematurely terminated due to harming patients.

One difference between these approaches is their effect on vitamin K activity in the body. Heparin does not interact with vitamin K, whereas warfarin does.

Warfarin is a commonly known “Vitamin K Antagonist” drug that functions by reducing vitamin K levels by impairing vitamin K recycling. Vitamin K is needed for making many coagulation factors and other necessary compounds, especially those used to grow and maintain bone. Warfarin disrupts production of these coagulation factors by lowering active vitamin K levels, but at the expense of causing many other health problems.

The study discusses other possible vitamin K related mechanisms to explain COVID-19 symptoms and outcomes. COVID-19 patients appear to have damaged elastic fibers in the lungs. It appears that vitamin K is involved both in processes for forming elastin for these elastic fibers and for mineral transport, especially of calcium, that keeps these fibers from being damaged by mineralization. A relevant quote from the study:
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Numerous Potential Treatments for SARS-CoV-2 Virus, COVID-19 Disease, and High-Risk Factor Comorbidities

Most recent update: July 29, 2020

FDA-approved treatments for the SARS-CoV-2 coronavirus and its resulting COVID-19 disease are scarce and poor quality, but scientists and doctors have found many potential treatments that look promising.

Part of the problem is that SARS-CoV-2 and COVID-19 are recent and there has not been enough time for in-depth research or clinical trials. However, as the SARS-CoV-2 virus is very similar to SARS-CoV and MERS-CoV coronaviruses, research done on those over the past decade or more is likely applicable.

Some promising options are already FDA-approved treatments for other conditions, but many may never be FDA-approved because they cannot be patented and sold for extreme profits. You may have to turn to alternative medicine practitioners or medical systems in countries less fascist than the US to get some such treatments.

This list is not intended to advocate for any of them or to prescribe anything for treatment. It is intended to refer you to information that discusses how various nutrients, herbs, pharmaceuticals, and other approaches may help people avoid infection or reduce risk for serious injury or death from viral infections.

Some of items on the list address nutrient deficiencies and high-risk comorbidities given the possibility that improving these conditions may reduce the risk of serious harm from COVID-19.

Please consult a competent medical provider and spend significant time of your own investigating anything listed here before trusting it is applicable, safe for you, and effective.

Every person is unique, with unique genetics and epigenetics, health status, diet, lifestyle, and environment. Therefore what works well for one person could be ineffective or even harm another.

The list will be updated as new information becomes available, so check back occasionally to see if there is something new.

General Background on Virus and Immune Support

Respiratory Immune Support: Focus on SARS-CoV-2 and COVID-19
Explains background information on virus including similar viruses and symptoms, available medical treatments, and provides brief information on several supplements that may be helpful.

Prevention and Treatment Recommendations Including Supplements As Suggested By Medical Doctors

How to Fix the COVID-19 Crisis in 30 Days
New data out of Europe shows that simply raising vitamin D3 levels may cut rates of severe COVID-19 infections and deaths to near zero. This article also discusses quercetin, zinc, magnesium, selenium, time-restricted eating, low-carb and cyclical ketogenic diets, and molecular hydrogen and how they all may help reduce risk from COVID-19.

Dr. Richard Bartlett Talks COVID Cures on American Can We Talk?
Dr. Richard Bartlett discusses the medicine Budesonide that he believes has enabled Taiwan, a nation of 25 million with close cultural ties to China, to have only 7 deaths in the COVID-19 pandemic. Part of his discussion is what has happened with rapid recoveries in his own patients to whom he is prescribing this medicine.

Eastern Virginia Medical School Critical Care COVID-19 Management Protocol
A detailed protocol document developed by Dr. Paul Marik, MD.

Two-page summary of EVMS Critical Care COVID-19 Management Protocol

COVID-19: Life-saving Strategies the New Media Will Never Tell You
Discussion of COVID-19 and its treatment by Dr. Paul Thomas MD.

Immune Support Supplements

Lactoferrin Helps Protect Against Viruses
Lactoferrin is a natural immune compound high in mother’s milk, especially colostrum. This article discusses lactoferrin’s broad effect in scientific studies against a wide range of viruses including SARS-CoV.

Immune-Boosting Effects of Melatonin
Melatonin is most well-known as a sleep-promoting hormone, but it also has many other effects including boosting immune system function in many ways.

Improving Mucosal Defenses Helps Resist Respiratory Tract Infections

Probiotic Phage Blend Fights Digestive Problems and Boosts Immune Defenses
Probiotics and bacteriophages can be used in supplement form to enhance mucosal barrier resistance to bacterial and viral pathogens and the mechanisms of action should work against pathogens in general. One study discussed evaluate effect on flu season infections and found (quoted from article):

The impact this probiotic treatment had on respiratory infections was not subtle! The number of flu and flu-like viral illnesses were reduced by an impressive 75%. The rate of colds—also a viral illness—was also reduced, by 39%.

Vaccines Raise Coronavirus Infection Risk

Pentagon Study: Flu Shot Raises Risk of Coronavirus by 36% (and Other Supporting Studies)
Flu vaccination raises the rates of coronavirus and non-influenza respiratory viral infections, thereby putting the population at higher risk of COVID-19 and other viral respiratory infections

Insulin Resistance Raises COVID-19 Risks

The Real Pandemic Is Insulin Resistance
Insulin resistance is a major risk factor for severe COVID-19 infections, especially deadly cytokine storms. People with type 2 diabetes are insulin resistant, but the problem in the US probably affects most of the population even if they have not been diagnosed with type 2 diabetes.

Air Pollution May Raise COVID-19 Risks

COVID-19 PM2.5: A national study on long-term exposure to air pollution and COVID-19 mortality in the United States
Results: We found that an increase of only 1 μg/m3 in PM2.5 is associated with an 8% increase in the COVID-19 death rate (95% confidence interval [CI]: 2%, 15%). The results were statistically significant and robust to secondary and sensitivity analyses.

Study Shows Link Between Fine Particle Air Pollution and COVID-19 Mortality
A Harvard study shows a statistical correlation between PM2.5 air pollution (particles 2.5 micrometers and smaller that can even get into bloodstream) and COVID-19 deaths.

For example, the study found that an individual living in a county for decades with high levels of PM2.5 is 15 percent more likely to die from the coronavirus than someone in a region with one unit less of the fine particulate pollution.

Problems With Mask and Social Distancing Recommendations

Scientists Find Coronavirus Can Linger In The Air Of Crowded Spaces Longer Than We Thought
WHO guidelines regarding when to wear a mask fail to account for virus staying airborne for long times

For social distancing to truly work, people would need to stand 26 feet apart, say researchers
New MIT study says that sneezes or coughs can create cloud of SARS-CoV-2 virus particles up to 23 to 27 feet from infected person, meaning 6 foot social distancing is not adequate for protection.

Hydroxychloroquine and Connections with Zinc, Zinc Ionophores, and Zinc-Deficiency Diseases

Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19
This study on hospital inpatients in the Henry Ford Health System in Michigan, United States, shows that hydroxychloroquine with or without azithromycin cut death rate significantly even in these very sick patients.

New York Dr. Vladimir “Zev” Zelenko Reports Success Against COVID-19 With Hydroxychloroquine, Azithromycin, and Zinc
Discusses early results using hydroxychloroquine, zinc, and azithromycin to treat COVID-19 patients in New York City

Surgisphere: mass audit of papers linked to firm behind hydroxychloroquine Lancet study scandal
“Credible” mainstream medical journals Lancet and New England Journal of Medicine were caught publishing studies to discredit hydroxychloroquine using apparently fake data claimed to have been from Australia, but none of the hospital had ever heard of the Surgisphere firm providing the data. Further investigation is uncovering other apparent scientific frauds related to the firm and its founder.

ASSOCIATION OF AMERICAN PHYSICIANS & SURGEONS, Plaintiff, v. FOOD & DRUG ADMINISTRATION; DR. STEPHEN M. HAHN, Commissioner of Food & Drugs, in his official capacity; BIOMEDICAL ADVANCED RESEARCH & DEVELOPMENT AUTHORITY; GARY L. DISBROW, Ph.D., Acting Director, Biomedical Advanced Research & Development Authority, in his official capacity; DEPARTMENT OF HEALTH & HUMAN SERVICES; and ALEX AZAR, Secretary of Health & Human Services, in his official capacity, Defendants.
A group of physicians sues US government officials who have interfered with the use of hydroxychloroquine to protect Americans from COVID-19.

Coronavirus: Debunking The Hydroxychloroquine ‘Controversy’ (Dr. Chris Martenson)
Some recent scientific studies are showing that hydroxychloroquine does not work but they are using incorrect treatment protocols that lack zinc that some doctors claim is necessary for the zinc ionophore effect of chloroquine to raise intracellular levels of zinc to slow or block viral replication.
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Health-boosting Drinks For Coronavirus Crisis

With COVID-19 racing around the global this year on top of the usual common colds (often caused by weaker coronavirus infections) and flus, you might be thinking it is time to boost your immune system with nutrition and supplements.

Vitamin C is a really important nutrient to keep your immune system strong. It is particularly helpful at boosting your immune system against viral infections. But some people have trouble swallowing tablets and capsules.

Mixing vitamin C into a beverage solves this problem. It also can spread out the vitamin C dosage over more time than taking a gram at a time in capsules or tablets, improving the amount that will be absorbed and reducing the odds of digestive upset such as diarrhea that can come from large amounts of vitamin C taken in a short amount of time.

The amino acids in collagen-rich foods such as bone broths are important to repairing vascular system damage such as what happens from high levels of systemic inflammation from a viral infection that leads to problems like abnormal bleeding due to leaks in small blood vessels. These amino acids also may help improve skin, nails, bones, and teeth.

The glycine in these collagen-rich foods is also important for liver detoxification processes. Most people probably do not get enough glycine in their diet and supplements each day, especially people who are eating “modern” diets that emphasize meat over complete animal protein including bone broths and connective tissues such as joints, skin, and “delicacies” such as chicken feet so loved by the Chinese.

However, making bone broths is time-consuming and it can be difficult and expensive to obtain high-quality bones unless you’re raising your own chickens or ruminants. Pre-made bone broths are expensive, especially if they are from organic bones.

Collagen powders are a great option for getting the amino acid nutrients you’d find in bone broths. They make it super-easy to add protein to many kinds of foods and drinks.

Making Vitamin C and Collagen Health-boosting Drinks

You can combine the vitamin C and collagen powder along with anti-viral ingredients to make various drinks that taste good and boost your health.

We often make simple health-boosting drink mixes with recipes along these lines:
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Is Online Shopping Safer In the COVID-19 Coronavirus Era? Will Your Amazon Package Kill You?

Will you get an infection with your package?

As the COVID-19 coronavirus spreads around the world, it has become clear it is highly infectious and hard to stop.

Much of the focus has been on person-to-person transmission. Certainly the use of quarantines and travel restrictions can help slow the spread.

Although airborne transmission has been viewed as the biggest risk, there are concerns about the coronavirus spreading via objects and surfaces touched by people and transmission via water and food.

Consequently, you may be wondering about the safety of buying products online, particularly if they originated from areas with virus outbreaks.

There are some surprises, one of them being that there are steps you can easily and inexpensively take to reduce risk.

Online vs. Local Shopping

Online, mail order, and phone shopping all reduce your person-to-person contact. That’s a good thing as the most likely way COVID-19 spreads is via airborne droplets and aerosols over short distances, with risk being highest within 2 meters (roughly 6 feet) of infected people.

Reducing the time spent around other people, the number of other people with whom you come into contact, and proximity will all help reduce your risk for infection and online shopping does all of that.

So if your local area has many cases of the virus, online shopping is highly likely to be safer because you’re less likely to be exposed to airborne virus coming from those who are infectious but may not even know they are infected.

But what if your local area has few cases and you are ordering from a large online retailer that has facilities in major outbreak areas?

The answer then largely comes down to how long can the virus last on surfaces. Fortunately, there is some good information coming from scientific research that helps to understand and reduce the risks.
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Congressional Representative Takano’s Office Mixes Facts With Anti-scientific COVID-19 Coronavirus Propaganda

US Congressional Representative Mark Takano’s (California) office recently sent out an email which attempts to relay information to the public about the COVID-19 coronavirus outbreak. Unfortunately, helpful information is mixed with disinformation that could lead to harm.

This email in its zeal to speak out against racism misinforms the public about the risks of COVID-19 infections.

Quote from Takano’s email:

Being Chinese or Asian American does not increase the chance of getting or spreading COVID-19.

People who have not recently traveled to China or been in contact with a person who is a confirmed or suspected case of COVID-19 are not at greater risk of acquiring and spreading COVID-19 than other Americans.

As a member of the Congressional Asian Pacific American Caucus, I urge you to please be respectful of your Asian American friends and neighbors. We cannot allow this public health emergency to lead members of our community to be targets of discrimination. Racism and xenophobia are not welcome or tolerated in our community.

While speaking out against racism is laudable, in this case it includes statements that appear to be inaccurate based upon current science and may cause harm.

Groups With Higher ACE2 Receptor Expression May Raise Infection Risk

China’s scientists are publishing data which appear to indicate that Asians, especially Asian males, are at higher risk for COVID-19 infection because of how they have more ACE2 (Angiotensis Converting Enzyme 2) receptors in their bodies than other ethnic groups.
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Do Not Rely On COVID-19 Coronavirus Vaccines, Protective Steps You Can Take Even Now

As 2019-nCoV aka COVID-19 spreads across the world, many are talking about vaccines like they are going to be a solution.

If you’re smart, you should not be counting on a vaccine to zero out your risk from COVID-19. Vaccines have risks and limitations.

There are many other steps you can take, whether or not you believe a vaccine is a good choice, that can help reduce your risks from COVID-19.

If you are already familiar with the many problems with vaccines for RNA viruses (such as COVID-19), toxic ingredients, current vaccine manufacturing technologies, and questionable safety testing, you may choose to skip down towards the end of this article to get to suggested steps you can take now.

Flu Vaccine As A Model For COVID-19 Vaccines

Consider flu vaccines to better understand why COVID-19 vaccines may be a poor solution.

COVID-19 is a lipid enveloped RNA virus like influenza virus. The immune system has a hard time seeing the proteins inside of the innocuous looking lipid layer. As an RNA virus, it mutates more rapidly than DNA viruses making it a moving target for vaccine development.

The virus circulating in a few months is likely to be different from what is circulating now, meaning the protein targets or viral strain(s) used in a vaccine may no longer match. Thus the antibody response generated would be against a virus that is not the strain spreading at the moment.

Flu vaccines often fail to target the currently circulating strains. Even government vaccine cheerleaders such as the CDC admit they are poorly effective if they do not include the strains that actually end up circulating during the flu season.

Even in a single infected person, an RNA virus may mutate fast enough that the strain replicating at the moment in the body significantly differs from the initial strain that established the infection.

Such observations may help explain the reports that some who recovered and tested negative for COVID-19 days go on to test positive for the infection at a later date.

You might think that being injected with the flu vaccine, even if it is ineffective, will not hurt you. But scientific research and medical opinion suggests that could be very wrong, for multiple reasons.
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2019-nCoV China Coronavirus May Be Genetically Engineered For Bioweapon Or Vaccine

Allegations that the 2019-nCoV coronavirus is a bioweapon are in the news as reports out of China worsen with skyrocketing numbers of infections and deaths, widening quarantines, the banning of funerals of coronavirus victims and requirements to rapidly cremate corpses, and even a report of a woman shot for trying to get through a quarantine roadblock.

Outside of mainland China, the Philippines and Hong Kong have reported their first deaths as other nations in Southeast Asia see rapid percentage increases in their reported infections.

Indian Scientists Report on Possible HIV-1 Connection

Researchers in India have discovered what to them appear to be HIV-1 virus (the virus usually blamed for AIDS) gene fragments in the 2019-nCoV virus. In their view, this is unlikely to have happened naturally.

Quote from Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag:

We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.

Some are pointing to this as evidence the 2019-nCoV virus was engineered from a SARS-like coronavirus enhanced with HIV-1 glycoproteins to make it more infectious and a better bioweapon.
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2019-nCoV Coronavirus May Spread Via Virus-Contaminated Surfaces

Media in China have announced that the 2019-nCoV virus may live outside the human body, such as on surfaces contaminated via coughs and sneezes:

Quote from Transmission ways of nCoV spark concern:

New ways of transmitting the coronavirus have been reported, and virus nucleic acid has been detected outside human bodies, sparking public concerns that the virus could be transmitted in unknown and undetected ways.

Scientists have found coronavirus nucleic acid on the doorknob of a confirmed Guangzhou-based patient’s house, the first case of novel coronavirus detected outside the human body, Guangzhou Daily reported Monday.

Mobile phone screens, computer keyboards, faucets and other household objects may indirectly transmit the virus, experts said.

The virus may remain potentially infectious on these surfaces for several days:

Quote from Discovery Of Coronavirus On Doorknob Of Infected Patient Sparks Transmission Concerns:

Concerns emerged after scientists found coronavirus nucleic acid on the doorknob of a confirmed Guangzhou-based patient’s house, the first case of novel coronavirus detected outside the human body, Guangzhou Daily reported Monday. The finding was confirmed by China’s Health Commission, which said on Monday that the coronavirus can survive for five days maximum on smooth surfaces under suitable circumstances.

Actions you can take to reduce transmission via such pathways include avoiding touching your face, mouth, or eyes with your hands, frequently washing your hands and washing them well, thorough cooking of foods, thoroughly washing dishes and utensils at high temperatures, and handling food, dishes, and utensils and serving or eating food only after washing your hands.

Packages or items that may be contaminated, such as packages shipped from areas with known infections, could be left outside your home for more than 5 days before being brought inside to reduce the risk of infection.

You could also spray items with an alcohol-based disinfectant or diluted bleach and then wait for them to dry before handling. A study from The Journal Of Hospital Infection found that such sprays can inactivate COVID-19 in about a minute.

You can find more details on disinfectant sprays tested along with more information on the risks and steps you might take for packages such as from online shopping via this link.

More Articles Discussing 2019-nCoV Coronavirus

Hidden Factors Behind High 2019-nCoV Rates of Transmissability and Mortality and What You Can Do About Them

As of January 31, 2020, the 2019-nCoV coronavirus case count has surpassed the last big outbreak of coronavirus in 2002-2003 in a fraction of the time.

Some point to this coronavirus being a bigger threat because one its surface proteins appear to be engineered via its encoding genes containing four short segments from HIV-1, the virus blamed for AIDS.

While genetic variations in this virus versus SARS could certainly explain a lot, there may also be environmental reasons for the rapid spread.

Wuhan, China, the epicenter of this viral outbreak was one of the first cities in China with widespread 5G wireless technology deployment. The Chinese news agency Xinhua reports the city was planned to have 10,000 operating 5G base stations by the end of 2019. It already had 1580 base stations in operation on China Mobile’s 5G network by mid-October 2019. Commercial service was launched October 31, 2019.

What does wireless technology have to do with a virus outbreak? On the surface, it may appear to be nothing.

But dig deeper, and connecting factors can be found in the separate research papers of Dr. Paul Marik, MD and Dr. Martin Pall, Ph.D.
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Could Coronavirus Spread Through US Sewage, Waterways, and Food Supply?

As of late on January 30, 2020, the official number of 2019-nCoV coronavirus infections is 9776 with 213 deaths. The US, Japan, Germany, Canada, and other nations have confirmed it is spreading in their countries via person-to-person transmission. Consequently, it is very likely the number of cases and deaths is going to continue to skyrocket for the foreseeable future.

While the focus so far has been on fears of transmissions from poor food safety in China and person-to-person transmission, there are other potential transmission pathways. Many viruses, including SARS and other coronaviruses, are shed through urine and feces.

Consequently, possible transmission paths for viruses are sewage, waters into which sewage flows, and anything these may directly or indirectly contact such as farm fields and water supplies. In the US, inadequately treated sewage sludge is turned into fertilizer that could end up contaminating food crops, so this is a significant risk.

If food and water can be contaminated, what might be done to reduce the risk? There are some ideas on this towards the end of this article.

Research on Coronavirus in Sewage

Live coronavirus in sewage is a demonstrated fact based upon studies done regarding the SARS virus.
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